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Lipoza® - Glutathione (Liposomal L-Glutathione)

Glutathione is the “The Antioxidant Master of Nature ” in the body because of its pivotal role in maintaining health and protecting cells from oxidative damage. It is the first line antioxidant in the human body to counteract the damage caused by the free radicals. LIPOZA – Glutathione is L-Glutathione supplement that utilizes liposomal technology for enhanced absorption and bioavailability. It protects L-Glutathione molecules as they pass through the digestive system.

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Role of Glutathione

Anti-oxidant

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Liver Health

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Skin Brightening

Benefits of Glutathione

  • Powerful antioxidant that supports detoxification, liver health, and cellular repair
  • Enhances skin health through brightening, collagen production, and improved hair and nail strength
  • Strengthens immunity and provides anti-inflammatory protection
  • Supports heart health, insulin sensitivity, and regulation of cellular processes
  • Promotes wound healing, nerve function, and helps manage diabetic neuropathy and rheumatoid conditions
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Dynamic Light Scattering (DLS) for particle size measurement

Dynamic Light Scattering (DLS) is employed to evaluate the particle size distribution and polydispersity of liposomal formulations, providing essential information on colloidal stability, dispersion uniformity, and potential bioavailability.
For example – Lipoza®-Curcumin

Zeta Potential Analysis for surface charge and stability

Zeta potential analysis provides insight into the surface charge and colloidal stability of liposomal formulations, where higher negative values indicate improved dispersion stability and reduced risk of particle aggregation.
For example – Lipoza®-VitC

Absorption and permeability through models like Caco-2 cell lines.

Caco-2 studies utilize human intestinal epithelial cell monolayers to evaluate the permeability and predicted absorption of test substances across the gut barrier.

For example – Lipoza-Glutathione
Demonstrated superior permeability, showing 0.95% transport compared to 0.29% for Reduced L-Glutathione—an approximate 3.28-fold increase. This enhanced permeability, despite lower glutathione content, indicates improved intestinal absorption and supports its potential as a more bioavailable form of glutathione supplementation.

1.TEM-Based Structural Analysis of Liposomal Formulations

Transmission Electron Microscopy (TEM) provides high-resolution visualization of liposomal morphology, enabling assessment of vesicle size, shape, and internal structure. Liposomes generally appear as well-defined spherical vesicles with a distinct bilayer and a darker core region.
For example – Lipoza®-Q10

2.SEM-Based Surface Characterization of Liposomes

Scanning Electron Microscopy (SEM) offers detailed visualization of surface morphology, enabling assessment of particle texture, external structure, and overall physical characteristics of liposomal powders. This technique helps confirm uniformity, surface smoothness, and morphological integrity of the formulation.
For example – Lipoza®-Fe
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